Grey’s Anatomy’s sixteenth season premiered on September 26, 2019. On ABC, the first half of the season aired on Thursday nights at 8 p.m. It began airing at 9 p.m. after the mid-season break, after Station 19. The season was supposed to include 25 episodes, however because of the COVID-19 outbreak, production was halted after filming on episode 21, which ended up being the season finale because production would not restart.
The season will follow the following storylines, according to showrunner Krista Vernoff:
The consequences of Meredith, Richard, and Alex being dismissed, as well as Meredith’s imprisonment.
Owen, Teddy, and Tom’s love triangle continues, as do Teddy’s challenges with parenting and Amelia’s attempts to figure out who she is.
Jo’s rehabilitation from psychiatric care.
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Various narratives on the United States’ immigration policies and the “broken” health-care system.
Meredith fights to save her medical license.
Dr. Meredith Grey is played by Ellen Pompeo (21/21). (Only one voice)
Justin Chambers (1 voice only) as Dr. Alex Karev (9/21) (until Leave a Light On)
Dr. Miranda Bailey is played by Chandra Wilson (19/21).
Dr. Richard Webber is played by James Pickens, Jr. (21/21).
Dr. Owen Hunt is played by Kevin McKidd (17/21).
Dr. Jackson Avery (19/21) is played by Jesse Williams.
Dr. Amelia Shepherd (17/21) is played by Caterina Scorsone.
Dr. Jo Karev is played by Camilla Luddington (18/21).
Dr. Maggie Pierce is played by Kelly McCreary (20/21).
Dr. Andrew DeLuca (17/21) is played by Giacomo Gianniotti.
Dr. Teddy Altman is played by Kim Raver (15/21).
Dr. Tom Koracick (16/21) is played by Greg Germann.
Dr. Levi Schmitt is played by Jake Borelli (17/21).
Dr. Atticus Lincoln is played by Chris Carmack (17/21).
Guest Stars Who Return
Dr. Catherine Fox is played by Debbie Allen (10/21). (1 voice only)
Barrett Doss (7/21) in the role of Victoria Hughes
Dr. Carina DeLuca is played by Stefania Spampinato (6/21).
Robin (3/21) with Cleo King
Dr. Dahlia Qadri is played by Sophia Ali (3/21).
Dr. Nico Kim is played by Alex Landi (11/21).
Nancy Klein is played by Devika Parikh (3/21).
Ben Warren (Jason George) (10/21)
Dr. Taryn Helm is played by Jaicy Elliot (13/21).
Gemma Larson (Jasmine Guy) (4/21)
Shirley Gregory is played by Lisa Ann Walter (2/21).
Dr. Casey Parker is played by Alex Blue Davis (5/21).
Bess Armstrong (1/21) as Maureen Lincoln
Eric Lincoln (1/21) is played by Granville Ames.
Paul Castello (1/21) is played by Mike McColl.
Luis Rivera (1/21) is played by Omar Leyva.
Patricia Murphy (1/21) is played by Robin Pearson Rose.
Ray Ford (1/21) as Ray Sutera
Katie Bryce (1/21) by Skyler Shaye
Pruitt Herrera (1/21) is played by Miguel Sandoval.
Dr. Cormac Hayes is played by Richard Flood (9/21).
Lieutenant Jack Gibson (1/21) is played by Grey Damon.
Dean Miller is played by Okieriete Onaodowan (2/21).
Elliott Calhoun (Richard Jin) (2/21)
Finley Calhoun is played by Adriana DeGirolami (2/21).
Suzanne Britland is played by Sarah Rafferty (3/21).
Hadley (3/21) is played by Lindy Booth.
Michelle Gardner (1/21) as Myrna Schmitt
Dr. Lauren Riley is played by Shoshannah Stern (2/21).
Maya Bishop (1/21) is played by Danielle Savre.
Heather McComb (1/21) as Rachel Burke
William is played by BJ Tanner. Jones, George Bailey (2/21)
Allison is played by Sherri Saum. (1/21) Robin Brown
Evelyn Hunt (1/21) is played by Debra Mooney.
Guest Stars of Note
Haylee Peterson is played by Alyssa Milano.
Heidi Peterson is played by Holly Marie Combs.